PFO · Randomized clinical trialCirculation · 2026
Transcatheter Closure of Patent Foramen Ovale With a Novel Biodegradable Device: A Prospective, Multicenter, Randomized Controlled Clinical Trial
Zhang F, Dong J, Wei P, et al., including Xiangbin Pan.
Authors include researchers from Fuwai Hospital, CAMS & PUMC, Beijing.
A multicenter randomized study of biodegradable PFO closure. Read the original paper with its published correction and discuss its relevance with your cardiologist.
DOI: 10.1161/CIRCULATIONAHA.125.074609PFO · Editorial perspectiveCardiovascular Diagnosis and Therapy
Bioresorbable patent foramen ovale closure—is less more?
Stefan Toggweiler and Mathias Wolfrum · Heart Center Lucerne, Switzerland.
A perspective on bioresorbable PFO closure. Commentary provides context and should be distinguished from the original clinical trial.
ASD · Related researchJAMA · 2025
Bioresorbable vs Metallic Occluders for Transcatheter Atrial Septal Defect Closure: A Randomized Clinical Trial
Ouyang W, Jiang H, Yan X, et al., including Xiangbin Pan.
This trial concerns atrial septal defect (ASD), a different condition from PFO. Its results should not be presented as PFO treatment outcomes.
VSD · Related researchScience Bulletin · 2023
Transcatheter closure of perimembranous ventricular septal defect using a novel fully bioabsorbable occluder: multicenter randomized controlled trial
This study concerns ventricular septal defect (VSD), not PFO. It is included as related research into bioabsorbable closure devices.
These are brief reading notes and source links, not reproductions of the articles. Inclusion does not imply author or institutional endorsement of China Hospital Access. Discuss medical decisions with your treating clinicians.